https://doi.org/10.3109/13693786.2011.574238

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Skin Test Reactivity of Allergic Subjects to Basidiomycetes' Crude Extracts in a Tropical Environment

Document Type

Article

Publication Date

11-1-2011

Abstract

Fungal allergies can be detected by the skin prick test with extracts of the organisms, but not all fungi, including the basidiomycetes, are being examined. We determined the level of sensitization to basidiomycetes in allergic subjects and compared their reactivity to commercial extracts commonly used to detect allergies. Crude spore extracts of the basidiomycetes Ganoderma applanatum, Chlorophyllum molybdites, and Pleurotus ostreatus, which are known to release numerous spores, were examined along with commercial extracts on 33 subjects with asthma, allergic or non-allergic rhinitis. Overall, affected subjects showed the highest reactivity to mites (36%), followed by Ganoderma applanatum (30%), grass (27%) Chlorophyllum molybdites (12%) and Pleurotus ostreatus (12%). Allergic rhinitis patients were most reactive to mites (58%), grass (42%), Ganoderma applanatum (25%), Penicillium spp. (25%), and cat (17%). Those with asthma primarily responded to mites (44%), Ganoderma applanatum (44%), grass (33%), and Pleurotus ostreatus (22%). IgE levels correlated with positive basidiomycetes extracts. This finding, coupled with higher reactivity to basidiospores as compared to mitospores, and the similar sensitivities of patients to G. applanatum and mites, suggest that basidiomycetes are important allergen sources in the tropics.

Publication

Medical Mycology

Publisher

Oxford University Press

Volume

49

Issue

8

Pages

887–891

Department

College of Arts and Sciences

Peer Reviewed

1

Publication History

Received: 25 October 2010 Revision received: 24 February 2011 Accepted: 17 March 2011 Published: 01 November 2011

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